Lindsay Shopland

Background

Dr. Shopland has a long history in biomedical research. Her career has spanned from managing in the biotech industry to clinical research in healthcare to teaching in academia. She has served on the faculties of the University of Maine and the Jackson Laboratory. Her broad experience allows her to expose students to a variety of career options, as well as share her extensive knowledge of biology.

Dr. Shopland’s current scholarly activities include research on endometriosis, a “hidden disease” that causes severe pain in women and has significant impacts on quality of life. She is working on methods to educate girls, parents, and health care providers to break cultural taboos surrounding menstruation and promote endometriosis awareness.

She has ample research projects available for Rivier students, ranging from surveying local populations to measure awareness and prevalence, to testing public messaging methods, to microbiology studies on reproductive tract microorganisms.

In the past, Dr. Shopland worked on immune therapies for cancer and molecular drivers of lymphoma. She investigated how the three-dimensional folding of DNA influences lymphoma cells. Dr. Shopland also examined how the fibrous scaffold of lamins in the cell nucleus influences DNA folding. To provide more effective treatments for lymphomas and breast cancer, she worked in clinical research to collect tumor specimens from patients and test their response to combinations of known cancer therapies.

Publications

• Shah, D., Soper, B., & Shopland, L. (2023). Cytokine release syndrome and cancer immunotherapies – historical challenges and promising futures. Frontiers in immunology, 14, 1190379.
• Pruvost, M., et al., (2023). The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina. Cell reports, 42(8), 112848.
• Curtis AD, Rueter J, Rajan, SS, Zhang R, and Shopland LS. (2018). Additive and synergistic inhibition of mantle cell lymphoma cell growth by combining olaparib with ibrutinib. J Cell Biochem. 119(7):5843-5851. doi: 10.1002/jcb.26773.
• Snow, K. J., et al., (2011). Nuclear positioning, higher-order folding, and gene expression of Mmu15 sequences are refractory to chromosomal translocation. Chromosoma, 120(1), 61–71.
• Shopland, et al., 2008. Journal of Cell Biol. 174(1): 27-38.